| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7ba32e0bf0d1093cf6c96a21ccfb7f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa65565ad129c6cc8a9aef88438d8451
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cf292a907da2d59312787e1edafa13e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7d5ea46e0fa64fcb21191e8975ae2fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f98255fe354f4c59b8aaa0556a833dc |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-26004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 |
| filingDate |
2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94a5ad6815be2c9095fb08804a213018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_241812768df5d203a25623cc95fa0a41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d19f9c2dd652bbfa5f4f796005eb66db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5818e726654c8f3cc9233e24a3effd48 |
| publicationDate |
2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012169916-A2 |
| titleOfInvention |
Sequence-specific engineered ribonuclease h and the method for determining the sequence preference of dna-rna hybrid binding proteins |
| abstract |
The subject of the invention is the ribonuclease which cleaves RNA strand in DNA-RNA hybrids, wherein ribonuclease comprises fusion protein comprising catalytic domain of RNase HI (RNase HI) or derivative thereof with a zinc finger DNA-RNA hybrid binding domain, and wherein the zinc finger binding domain has the ability to bind to specific sequences in the DNA- RNA hybrid. The invention also relates to new method for determination of the sequence preference of DNA-RNA hybrid binding protein(s) or its domain(s) and allows determining the sequence recognized by sequence specific binding protein in the DNA-RNA hybrid. |
| priorityDate |
2011-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |