| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9856cd5d7a57b8d134935597c6b110a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01f1be48d9b96a3bcc32fa862d9fad31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c80182fba21b2a79a8aae6aa049417e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94b937e8e80d0ccbde00f2090390a7a4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-60 |
| filingDate |
2011-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d87dbc19d0f697237ca5b4b40e47a8b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0759426e658e1e3c5571d022e80bcd1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e602754bb31e663de6dd0157ec3c486 |
| publicationDate |
2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012167406-A1 |
| titleOfInvention |
Method for preparing optically pure (+)-ambrisentan and (+)-darusentan |
| abstract |
Disclosed is a method for preparing optically pure (+)-ambrisentan and (+)-darusentan, comprising: firstly catalyzing the asymmetric epoxidation of a B-unsaturated alkene using a chiral ketone derived from fructose or a hydrate thereof as a catalyst, and then subjecting the product to an epoxy compound ring-opening reaction and substitution reaction successively to obtain optically pure (+)-ambrisentan and (+)-darusentan. |
| priorityDate |
2011-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |