| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f62b36b442d05acbbbd8a50348777098
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_720f1087535e6dbdab52352eaacf800d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-604
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-603
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-602
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-606
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1307 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate |
2012-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4fe1478eb698507c798aae35ffbe2d0 |
| publicationDate |
2012-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012166973-A1 |
| titleOfInvention |
Methods for promoting cell reprogramming |
| abstract |
The present invention is based on the seminal discovery that several kinases play important roles in barrier pathways in somatic cell reprogramming. The present invention provides that modulating expression or activity of these kinases can significantly promote or enhance cell reprogramming efficiency. Key kinases are identified and key regulation networks involving such kinases are also identified that may be advantageously targeted to significantly increase reprogramming efficiency as well as direct differentiation of induced pluripotent stem (iPS) cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111646997-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106243196-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110463688-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018057782-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111646997-A |
| priorityDate |
2011-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |