| abstract |
The present invention relates to a secretory fusion protein for target tracking, and more specifically, to a secretory fusion protein for target tracking comprising: a peptide with extracellular secretion; a molecular imaging reporter or a therapeutic peptide or protein; and a peptide which has a specific binding capacity to a target cell. According go the present invention, as the secretory fusion protein for target tracking can be prepared to comprise a peptide with extracellular secretion, a molecular imaging reporter or a therapeutic peptide or protein, and a peptide which has a specific binding capacity to a target cell, the fusion protein can specifically bind to a target cell, and binding occurrence can be checked by imaging. In addition, the fusion protein expression can be induced using an induction promoter, only when needed. Furthermore, it is possible to search for a therapeutic agent capable of treating the target cell using the therapeutic peptide or protein. Therefore, the secretory fusion protein for target tracking of the present invention is considered to be useful as a molecular imaging diagnostic agent or a tumor cell therapeutic agent. |