Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d79aaa205a2b1eb126d0ab39323de22a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb29fb3b3d95e4c68deade8f77bf9051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c3e900a79f68494cd44b3917a3a96d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db628fbc812ea146bb6eb24a8c0ab43a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75f05c8a44461c3c54eb79491f9d46b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93c5355e293c0aa4f4600b9a1ce86414 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
filingDate |
2012-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_802114a3699b83b2f3d2d532642bb513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_155f7ae0af7b6802d748acb623f0c23a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_111cdc83bd5dcf6e1af0234357238e7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4b194d7bb01b6ec53f781b8bbf1e968 |
publicationDate |
2012-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2012160337-A1 |
titleOfInvention |
Sulfated oligosaccharides for use in treatment of neurodegenerative diseases |
abstract |
Compounds which interact with Hl s TONES Compounds of Formula I : • 4"'-Sulfo-Fucose [alpha]1-3 (4"-sulfo)-Fucose [alpha]1-3 (4'-Sulfo-Fu- cose [alpha]1-4-Glucuronic acid [beta]1-0-Methyl or • 4" "-Sulfo-Fucose [alpha]1-3 (4"-sulfo)-Fucose [alpha]1-3 (4"-sulfo)- Fucose [alpha]1-3 (4'-Sulfo-Fucose [alpha]1-4-Glucuronic acid [be ta]1-0-Methyl. wherein X is sulfate (-SO 3 H) or phosphate (-PO 3 H); Su is sulfate and sulfation is most likely at the arrowed positions. The compounds above are useful in the inhibition of histones, in particular histone H1. The compounds can be used in medicine and particularly in the prevention and/or treatment of a wide variety of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021517582-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108392485-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7359396-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015038061-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111479574-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3723768-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019113645-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108392485-B |
priorityDate |
2011-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |