http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012150325-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f46b9a7a7fb0349640c1efa49a4dba8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d49723bcf7313c5c36b18f482e488849 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b04db5817ab462ea5a7eba3968df8ff1 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92 |
filingDate | 2012-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67b7f5145ec0bdb55ed2f3e426f3cfb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eb1595e4d1faff52da5e81b82b3d2c3 |
publicationDate | 2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2012150325-A1 |
titleOfInvention | Method for finding active pharmaceutical ingredients for the treatment of diseases associated with increased or decreased cytokine pathway activity |
abstract | The invention relates to a method for finding an active pharmaceutical ingredient potentially suitable for the treatment of a disease associated with increased or decreased cytokine pathway activity, comprising the steps of A1) providing a first lipid profile by a) providing a cell culture medium comprising cells having cytokine receptors, b) adding a pro-inflammatory cytokine to the cell culture medium c) adding a component that is potentially suitable for the prevention, treatment or co-treatment of a disease associated with increased or decreased cytokine pathway activity to the cell culture medium and d) determining the lipid profiles of the cells and/or of the cell culture medium to obtain the first lipid profile, A2) providing a second lipid profile by performing step A1) except for sub-step c) to obtain the second lipid profile, B) comparing the first lipid profile to the second lipid profile and C) identifying the component that was added in the method that shows a difference between the first lipid profile and the second lipid profile as the active pharmaceutical ingredient. |
priorityDate | 2011-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.