http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012149175-A1

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filingDate 2012-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2012-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2012149175-A1
titleOfInvention Means for determining depth-resolved physical and/or optical properties of scattering media
abstract In depth-resolved imaging of scattering media, incident light interacts with tissue in a complex way before the signal reaches the detector: Light interacts with media between the light source and a specific depth, then scatters at that depth and the back scattered light again interacts with media, on its way to the detector. The resulting depth-resolved signal therefore likely does not directly represent a physical or optical property of the media at those depths. According to an exemplary embodiment of the present disclosure, systems, methods and computer-accessible medium can be provided to determine physical or optical properties based on such a depth-resolved signal. For example, almost all the light can interact with the media, and that the energy of the incident light at a certain depth is likely therefore related to the integral of the scattered light from all deeper locations. Based on the detected signals, the properties of the media can be estimated in an iterative way. The exemplary system, method and computer-accessible medium can be used together with, e.g., retinal optical coherence tomography data, facilitating the calculation of depth-resolved attenuation coefficients. It is possible to, e.g., transform data resulting from complex interactions of light and media at a range of depths into data representing a decoupled physical or optical property of the tissue at a range of depths.
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