| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_006e91eddabe95ad7aa889123d31cb9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3286cbc69c5b65eda88c2ecce8645797 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6849
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-537 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-14 |
| filingDate |
2012-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9215fe2ac526c3141210173f935658be |
| publicationDate |
2012-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012145112-A2 |
| titleOfInvention |
Novel maytansinoid derivatives with sulfoxide linker |
| abstract |
The invention relates to novel maytansinoid compounds having sulfoxide linkers and more specifically to novel maytansinoid compounds of structural formula (I) and (II). The invention also provides conjugates of the maytansinoid compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016510730-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10640508-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014134457-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3699200-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016501859-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10918735-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2922818-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2922818-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9901647-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535634-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10918627-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10131682-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014134486-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105849086-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014134457-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105849086-B |
| priorityDate |
2011-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |