Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81ad53b64eb74859acdc01278829b080 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e40d73555b988e4cb5b6af42895d8aab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dad5a6969d9c5113e87638a276760926 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-54 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57446 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate |
2012-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30a4aba974b80e0b56b35f4801aeb9fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1a242fd7601a06b4db0c40f718ad2a8 |
publicationDate |
2012-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2012138785-A1 |
titleOfInvention |
Methods for predicting and improving the survival of gastric cancer patients |
abstract |
The present invention provides assays and methods for predicting the post-operative survival of a subject having an early stage gastric cancer after tumor surgery. The present invention also provides methods for treating a subject having an early stage gastric cancer by administering a combination therapy tailored to the signal transduction biomarkers that are activated in the cancer. In particular embodiments, the methods of the invention rely on the detection of the activation state or level of a specific combination of signal transducer analytes in a cancer cell obtained from the subject. Thus, the methods of the invention are particularly useful for predicting the survival or prognosis of a subject having an early stage gastric cancer and for guiding both pre- and post-operative treatment decisions by identifying subjects who would benefit from combination therapy as opposed to monotherapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113164480-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019150043-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017195887-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016501027-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3881847-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020092860-A1 |
priorityDate |
2011-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |