| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea30dcc02e2a72189cdd5bb6bf17685f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98ac0842ee7d782cf5bc19675ebb96c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bdb73c3d1e17f70327ed1e2303538f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_928be596aab39895c5b1ffd7632406a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d1750b578ca9a780678f6b9b9c8b87d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1870853a9b67b79ff4b64d57ce687b4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c00eaa97dd6a5bcecb49f685aea29fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50a14c89f7becc150b16142688a6a34a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-126
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1872 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12 |
| filingDate |
2011-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20d4e93ba3953403e059879ef65e1238
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c5c86c2418da519a036618efb59f9ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a2b0fe17b4aff02d8e0d451b51ac1d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03e3a33b62bf742c37fe55cd51f425af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85a0c94b485e47c0a1f7fed1979be948 |
| publicationDate |
2012-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012137999-A1 |
| titleOfInvention |
High-sensitivity magnetic resonance imaging nano-contrast agent based on an anionic polymer and cationic polymer ion complex, and a production method therefor |
| abstract |
The present invention relates to a nanocomposite containing anionic and cationic polymers and to a production method therefor. And the invention relates to a complex of poly-γ-glutamic acid (γ-PGA)/chitosan/manganese iron oxide nanoparticles which is produced by enclosing iron-oxide-based nanoparticles in a γ-PGA/chitosan polymer complex by using the ionic self-assembly properties of poly-γ-glutamic acid (γ-PGA) and chitosan which are biocompatible polymer substances, and the invention relates to a production method for the complex. By exploiting ionic assembly using the anionic poly-γ-glutamic acid (γ-PGA) and the cationic chitosan according to the present invention, the iron-oxide-based nanoparticles, which are confined in the polymer complex by being enclosed in the complex, give rise to a synergistic effect in magnetic resonance signal amplification due to interaction between each other, and thus the iron-oxide-based nanoparticles have a far better contrast effect than when present as single particles. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10940217-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3119203-A4 |
| priorityDate |
2011-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |