| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e950fb3ebb510bda9d8868f93116a13d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c832a29d737f977f91112c4723e9cfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_100fa99ecdbbeb11f7063f1e39c7b5b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb8f3eba86915d967beefc175437273a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84fc06afed26dcf90381233e546ad475 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F1-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-82 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N55-02 |
| filingDate |
2012-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39e5edc2928e200509a5381eceb939c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f0e4eaf84a4f21ba697298b3becf4a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8ae7275828de59c93348d4d5dc82a1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e7931f5e59ae8e22dd2c4977c888d78 |
| publicationDate |
2012-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012134822-A1 |
| titleOfInvention |
Allosteric reversible pan-caspase inhibitors |
| abstract |
The invention provides a method for the use of a group of compounds as allosteric reversible caspase inhibitors. This invention is in the field of medicinal chemistry and relates to novel compounds, and pharmaceutical compositions and methods of use thereof that inhibit caspases and/or tumor necrosis factor alpha (TNFa) that mediate cell apoptosis and inflammation and inhibit pathophysiologic effects of excessive amounts of TNFa. The invention also relates to methods of using the compounds and pharmaceutical compositions of this invention to treat diseases where caspase and/or TNFa activity is implicated. The present invention also relates to methods for the use of allosteric, reversible pan-caspase inhibitors with pyridinyl, copper-containing molecules with a multi-ring structure. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11033579-B2 |
| priorityDate |
2011-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |