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filingDate 2012-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4beb894f5515f586c2c90f0f635f7979
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publicationDate 2012-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2012133814-A1
titleOfInvention Therapeutic agent for cancer, and method for determining prognosis of cancer
abstract Disclosed are: a novel therapeutic agent for cancer such as esophageal squamous cell carcinoma; a method for determining the prognosis of caner; and a method for detecting cancer such as esophageal squamous cell carcinoma or determining the prognosis of the cancer using a sample that can be collected non-invasively. The therapeutic agent for cancer comprises an antibody capable of performing an antigen-antibody reaction with FGFRL1 to inhibit the proliferation of cancer cells or an antigen-binding fragment thereof as an active ingredient. The method for determining the prognosis of cancer comprises determining the amount of expressed FGFRL1 in a cancer tissue separated from a living body, wherein it is determined that the prognosis is bad when the amount of expressed FGFRL1 is large. The method for detecting cancer comprises measuring FGFRL1 or a fragment thereof extracted from a biological tissue or FGFRL1 or a fragment thereof in blood separated from a living body, wherein it is determined that cancer is developed when the concentration of FGFRL1 or the fragment thereof is higher than that in a tissue or blood from a normal person.
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