| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0493227b04991de53e519ae85fc7200a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa0e2b593752400652c8b0b8280b3ab9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2817954cd008bcd609a4c4eb49050be |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9121 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate |
2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41c1ebbc703f2413cb97eeffa6057c28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4f81ec75a046f1ec5ce97238cdd552a |
| publicationDate |
2012-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012130984-A1 |
| titleOfInvention |
Kinases labeled in the c helix for the screening of inhibitors |
| abstract |
The present invention relates to a kinase containing exactly one label in the C helix, (a) wherein said label is a fluorophore, a spin label or an isotope label, (a)(i) wherein said fluorophore and said spin label are covalentiy bound to a thiol group or side chain amino group of an amino acid residue of said C helix, (a)(ii) wherein said isotope label is a moiety comprising one or more atoms which are isotopes with non-zero nuclear spin, said moiety being covalentiy bound to a thiol group or side chain amino group of an amino acid residue of said C helix, or said isotope label is an amino acid residue of said C helix, said amino acid residue comprising one or more atoms which are isotopes with non-zero nuclear spin, wherein said isotopes with non-zero nuclear spin are enriched as compared to the natural occurrence thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2810648-A1 |
| priorityDate |
2011-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |