http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012121523-A3

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filingDate 2012-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31a63c7bae783f2804fc709b65fece88
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publicationDate 2012-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2012121523-A3
titleOfInvention Process for preparing pharmaceutical formulation in form of antioxidant-free solution for injection containing pemetrexed or its salt
abstract The present invention provides a method for preparing a pharmaceutical formulation in the form of an antioxidant-free solution for injection, the method of which comprises: (a) controlling a dissolved oxygen concentration in a solution for injection comprising pemetrexed or its salt to 1 ppm or less; and (b) filling a container for injection with the solution obtained from the step (a), in a closed system having an oxygen partial pressure of 0.2 %v/v or less.
priorityDate 2011-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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