http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012118819-A3

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filingDate 2012-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85d44c71706e3acd035f0b4f954333df
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publicationDate 2014-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2012118819-A3
titleOfInvention Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same
abstract Provided according to some embodiments of the invention are methods of forming co-condensed silica particles. In some embodiments, the methods include reacting a thiol-containing silane and a backbone alkoxysilane in a reaction solution that comprises water to form thiol-functionalized co-condensed silica particles, wherein the thiol-functionalized co-condensed silica particles include a polysiloxane matrix and at least some of thiol groups are present within the polysiloxane matrix; and reacting the thiol-functionalized co-condensed silica particles with a nitrosating agent to provide the S-nitrosothiol-functionalized co-condensed silica particles. In some embodiments, provided are S-nitrosothiol-functionalized co-condensed silica particles.
priorityDate 2011-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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