http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012112675-A2

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publicationDate 2012-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2012112675-A2
titleOfInvention Layer-by-layer quantification of the remodeling of the human fovea in neurodegerative disease
abstract A system and method for layer-by-layer quantification of the remodeling of the human fovea comprises finding a fixed reference point in inner retina, measuring the thickness of the inner retina at the fixed reference point, for a range of finely sampled distances starting from the fixed reference point, measuring the thickness, comparing the measured thickness with a normative base and obtaining a plurality of curves, evaluating area for each curve and defining a distance from the fixed reference having highest sensitivity with respect to the fixed reference point compared to the normative base, displaying a 3D re-creation of foveal architecture-based color- coded picture in accordance with the measured thickness at each finely sampled distance, entering the measured thickness into a model having parameters, obtaining numerical solutions for each parameter, and defining percent change of the parameters for the patient versus the parameters for the control.
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