abstract |
The invention relates to in vitro methods for the detection of an autoimmune disease or of a high-risk pregnancy in a subject, or for the determination of the predisposition of a subject to develop an autoimmune disease, to develop a high-risk pregnancy or to experience an implantation failure, comprising the determination of the presence of and/or the measure of the quantity of anti-CD 146 auto-antibodies in a biological sample of the subject and comparison to a control value. |