| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3739ea954ea4c0cf92e2f1cda7e8696a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e44d50d6cfde8d8c4f7694059c62b59 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-7703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-553
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-45 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-272
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N35-00693
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-05 |
| filingDate |
2011-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36335c4d06846628715889e6a92790dd |
| publicationDate |
2012-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012087840-A1 |
| titleOfInvention |
Dispersion injection methods for biosensing applications |
| abstract |
I Injection methods for determining biomolecular interaction parameters such in label-free biosensing systems are provided. The methods generally relate to analyte sample injection methods that generate well-defined analyte concentration gradients en route to a sensing region possessing an immobilized binding partner. The injections conditions are generally established according to a set of rules that create a dispersion event that can be accurately modeled by a dispersion term. The dispersion term is incorporated into the desired interaction model to provide a reliable representation of the analyte concentration gradient profile, The resulting interaction model is then fitted to a measured binding response curve in order to calculate the interaction parameters. Thus, the injection methods described herein provide a continuous analyte titration allowing a full analyte dose response to be recorded in a single injection in contrast to the standard multiple injection approach |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018202994-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020120996-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018193666-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9990464-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3065885-A1 |
| priorityDate |
2010-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |