Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_af9fee1818d74debbba0d4ae6814928c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_13ef81df0ca335c8f9fcec7174d2d795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff70c575aed82133de94653bfec32787 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-385 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43 |
filingDate |
2011-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5e282dabe057a0892846eff7bc65943 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_045ff7ea1c7b2a8087ab00394205430d |
publicationDate |
2012-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2012083382-A1 |
titleOfInvention |
Conjugates of acyl homoserine lactone and catalase a from pseudomonas aeruginosa |
abstract |
The present invention is directed to an acyl homoserine lactone and catalase conjugate wherein the acyl homoserine lactone is N -3-(oxododecanoyl)-L-homoserine lactone (OdDHL) or butyryl L-homoserine lactone (BHL) and the catalase is a P. aeruginosa KatA protein or an antigenic portion thereof. The conjugate is used to treat P. aeruginosa infections by limiting the formation of biofilms and inhibiting a range of quorum-sensing dependent virulence factors by having an immunogenic conjugate provided as a therapeutic or prophylactic vaccine. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105548058-A |
priorityDate |
2010-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |