| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_721d5282e21dc8ef95befc95e7c81765
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47245a78d7b8566e7c2514e4709e599f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75e1b72d391ad33e9821bd80ff38b1c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa1bb290d8b1c0aa6d33829fcc7bc65a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c18ba6b5a2e42fbc7fc3017f50a6bb6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3d16c67ed09ef8bb09a0ecad48c866ae |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2821 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6812
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
| filingDate |
2011-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_babcacc2510075fbf070c4eb44eb49e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a83df3e97b13361dfae0cd15c419e8d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfb57462994a4ade90f5888dd40d6701
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1701c148a390f7a0515daf0673474ce6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1575485ba83483bac1321624f2b3dba |
| publicationDate |
2012-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012081433-A1 |
| titleOfInvention |
Biomarker for amyloid-β-related neurological disorders |
| abstract |
To provide a novel biomarker for use in the examination of amyloid-β-related neurological disorders such as Alzheimer's disease. [Solution] A method for examining Alzheimer's disease characterized by measuring the level of MFG-E8 protein in a blood, serum or plasma sample obtained from a subject person or animal and using the obtained measurement as an index for diagnosing Alzheimer's disease is disclosed. MFG-E8 protein was found as a protein binding to phosphatidylserine in a Ca 2+ -dependent manner in the supernatant of culture of cerebral neurons of a mouse model of dementia stimulated with Aβ 42 . Further, it was revealed that the level of MFG-E8 protein increases in patients with Alzheimer's disease. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020085547-A1 |
| priorityDate |
2010-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |