| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_986d0ab29fa7910a46cd21a12d682fe4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_920aeb951d45b22185e0c7dcead18588
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37024ab783c4f35f35c0e386690473d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e115f0f5508ddf03bae8fe33c4b0623a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c20078557dbe93b26c7c2fc75408bee |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0636 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-50273
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502738
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G05B15-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6832
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-327
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N25-4873 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-02 |
| filingDate |
2011-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a89960515cc93ee353194e23b5c53a84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_523314f3bc6db00c59b38544d55162cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b614c58ac60d928d15936bc69a4a3fa |
| publicationDate |
2012-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012076350-A1 |
| titleOfInvention |
A biosensor using impedimetric real-time monitoring |
| abstract |
A method an system is disclosed for the detection and/or allocation of at least one point mutation in target DNA and/or RNA duplexes. The method comprises obtaining a functionalized surface which is coated with probe DNA and/or RNA whereto target DNA and/or RNA duplexes are attached, contacting said functionalized surface to an electrolytic solution having a neutral pH in a flow cell and measuring a first impedance value within said electrolytic solution, and then adding a chemical to the electrolytic solution which is able to achieve denaturation of the target DNA and/or RNA. The method further comprises measuring a second impedance value within the flow cell after completion of the denaturation of the DNA and/or RNA target, and then obtaining a value representative for the impact of the chemical on the impedance of the electrolytic solution. The amount and/or allocation of point mutation(s) within the target DNA and/or RNA is then determined by calculating the denaturation-time constant based on the difference between the first and second impedance value and taking into account the impact of the chemical by third impedance value. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9075041-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9874538-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11015219-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10942146-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10041905-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10011549-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9766197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11561198-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9910008-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018119215-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10379080-B2 |
| priorityDate |
2010-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |