Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9ca0632596f3342a71f604d9152b9e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60c80db0a6f88c14c87751a2ac5425f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d211064bf75141a73b19398776ef0eb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4afb8b01aa8de7e0b24a86713b23a18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff3f1a1bb1e1520168826c1b26333b99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b94f819a268874bdce2c6a0e43ebd4ed |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-51 |
filingDate |
2011-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3210f47eb6cb4fe0994ee11f41ab9170 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cef2026f623db9c971440e3a4dd173d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbd58e70d46fc391cbc7028543a5f93b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab124bdc7e7fa2d7a231263b38e03a17 |
publicationDate |
2012-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2012072715-A2 |
titleOfInvention |
Use of prokaryotic sphingosine-1-phosphate lyases and of sphingosine-1-phosphate lyases lacking a transmembrane domain for treating hyperproliferative and other diseases |
abstract |
The present invention relates to the use of prokaryotic sphingosine-1 -phosphate lyases (S1PL) and S1PLs that lack a transmembrane domain or of a nucleic acid encoding such an S1PL in the prevention or treatment of a disease condition associated with elevated levels of sphingosine-1 -phosphate (S1P), and for which S1P elevation is directly or indirectly causative. In addition, the invention relates to a new product in the form of S1PL lacking the N-terminal loop domain. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103301163-A |
priorityDate |
2010-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |