| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_982ac68472a096dc09f13bc0811e89a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f234540867084737ca19a12a8622c852 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-54 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-47 |
| filingDate |
2011-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a37cc78a2bfca0a124281571d509153b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ef908ef96cbb84d3cd776676ad91460 |
| publicationDate |
2012-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012071420-A1 |
| titleOfInvention |
Enzyme combinations to reduce brain tissue swelling |
| abstract |
Tissue fixed charge density (FCD) is identified as another potential therapeutic target for reducing brain tissue swelling. Reduction of the FCD could reduce the thermodynamic force driving water entry into the brain. The present invention discloses chondroitinase ABC (ChABC) reduces tissue FCD and reduces tissue swelling, indicating that it may be an effective treatment to reduce edema and control intracranial pressure. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021221782-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021183675-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021183207-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019060425-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023081715-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020068261-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020263399-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021061648-A1 |
| priorityDate |
2010-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |