| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30eef18c8d3e3521de1bfc6922519d75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b951bb0dd4577a7f02fab570f443583c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36b2e28131fe86bd4f16fd85ea41343b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D271-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 |
| filingDate |
2011-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be5876557ea771de4f6c993782968298
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2440071ab29a35e00f843b4b4c241872 |
| publicationDate |
2012-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012069620-A1 |
| titleOfInvention |
Nitric oxide donors in therapy of nitric oxide deficiency-induced disturbances of cerebral microcirculation |
| abstract |
The present invention relates to nitric oxide releasing compounds and their use in the prevention, amelioration and/or therapy of nitric oxide (NO) deficiency induced disturbances of the cerebral microcirculation. The NO deficiency induced disturbances of the cerebral microcirculation may be due to an intracranial hemorrhage or stroke and can cause cerebrovascular spasms (or cerebral vasospasms) (CVS) and/or malperfusion of brain parenchyma caused by blood vessel and blood flow dysregulation which, in turn, can cause secondary neurological deficiencies (DIND) and/or brain infarction. Particularly, the present invention relates to the prevention, amelioration and/or therapy of delayed cerebral vasospasm- associated disorders after survived subarachnoidal hemorrhage by applying a NO-donor, most preferably Molsidomine. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10918643-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018243314-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017046304-A1 |
| priorityDate |
2010-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |