| titleOfInvention |
Compound ethyl 8-oxo-9-[3-(1h-benzimidazol-2-yloxy)phenyl]-4,5,6,7,8,9-hexahydro-2h-pyrrolo[3,4-b]quinoline-3-carboxylate, salt, crystalline form, cocrystal, formulation, processes for preparation, application as medicaments, pharmaceutical compositions and new use particularly as inhibitor of aurora kinases |
| abstract |
The invention relates more particularly to a new salt, cocrystal and formulations of ethyl 8-oxo-9-[3-(1H-benzimidazol-2-yloxy)phenyl]-4,5,6,7,8,9-hexahydro-2H- pyrrolo[3,4-b]quinoline-3-carboxylate of formula (F) to preparations thereof and to the use thereof therapeutically, particularly as selective inhibitors of Aurora A and B kinases, and for their use as anti-cancer agents. |