| abstract |
The present invention provides a nanopore sensor of sub-nanometer thickness. The nanopore sensor comprises: a second electrophoresis electrode or micropump (14), a second storage chamber (12), a second micro-nanometer separation channel (8), a base plate (1), a sub-nanometer functional layer (3), a first micro-nanometer separation channel (7), a first storage chamber (11), and a first electrophoresis electrode or micropump (13) disposed in sequence; a base plate opening (16) and a nanopore (5) are provided respectively at the centre of the base plate (1) and the sub-nanometer functional layer (3). A first electrode (9) for measuring ionic current is provided in the first micro-nanometer separation channel (7), and a second electrode (10) for measuring ionic current is provided in the second micro-nanometer separation channel (8). The method for preparing the sub-nanometer functional layer with nanopores in the present invention is easy; it solves the problem of the interaction between a basic group and the nanometer functional layer; and can distinguisha single basic group. |