http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012064229-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7bc3de29f31cf653d84cc5b86cb5b01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e275a6ba1049406e77231e7bb10f17ab |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-32 |
| filingDate | 2011-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df656bddb526ad5c140f263345f20750 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1748315445183f29911014cf9112a6c0 |
| publicationDate | 2012-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2012064229-A1 |
| titleOfInvention | Method for producing dihydroquercetin |
| abstract | The invention relates to the chemical and pharmaceutical industry. The essence of the invention is that Siberian or Dahurian larch wood is stripped of bark, chopped up and dried at 40-50°C to a residual humidity of 15-25%. The dried wood is ground and the soluble substances are extracted from the sawdust using a 75% aqueous solution of ethyl alcohol at a temperature of 40-50°C with a raw material to extractant ratio of 1:(6-7). The extractant is then distilled off and the aqueous portion of the extract is cooled to 38-42°C over a period of 20-30 minutes for the removal (sedimentation) of the heavy resinous impurities accompanying the dihydroquercetin (DHQ). The resin-free aqueous DHQ extract is fed into a chromatographic column filled with the hydrophobic polyvinyl benzene-based sorbent LPS 500. The target product is eluted with a 32-40% aqueous solution of ethyl alcohol. The eluate is collected in a single portion or is divided into two to three fractions depending upon the required purity of the target product (DHQ). Each fraction is evaporated until the ethyl alcohol is completely removed, and the residue is crystallized from deionized water. A target product with a 95.5-99.5% degree of purity is obtained with a yield of 1.5-2.5% from the mass of absolutely dry wood. The technical result includes simplifying the method, increasing its environmental friendliness and reducing its duration while increasing the purity of the target product to 99.5%. |
| priorityDate | 2010-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.