Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0773de5dd6ed591fb0989126493b09c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_562e4af016953c0a80e09960559ed0d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd68ae51587f8df5142c5f4334c69b10 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-208 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
filingDate |
2011-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26c6ab967f3c841968e8a16a1a15d1d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f58476e8e54ccb4bf4ec9a7482838f53 |
publicationDate |
2012-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2012058616-A2 |
titleOfInvention |
Engineered kinetochores and uses thereof |
abstract |
The invention provides modified DNA-binding kinetochore polypeptides, wherein the modified DNA binding kinetochore polypeptides comprise a heterologous DNA binding domain. The invention further provides engineered kinetochores containing the modified kinetochore polypeptides. Further provided are artificial chromosomes containing an engineered kinetochore. Cells containing an artificial chromosome containing an engineered kinetochore are also provided. Methods for producing and methods of using the engineered kinetochore, artificial chromosome, and cells are also provided. |
priorityDate |
2010-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |