abstract |
The invention provides a controlled-release oral pharmaceutical composition of at least an active agent, comprising : a) a lipophilic matrix consisting of lipophilic compounds and/or amphiphilic compounds; b) an hydrophilic matrix, wherein the hydrophilic matrix comprises at least an indigestible polysaccharide, the active ingredient being dispersed in the lipophilic and/or the hydrophilic matrix. The present invention also relates to a process for the preparation of such a pharmaceutical composition. |