| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20540c98f3275695fd8fb1e71a74b973
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3b8f7cdc402a43d3994bf920e8476a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90ef160e824db4a7249b1cefcac96e44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da9d0a191835d2aeb26914d52f3be552 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-35 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 |
| filingDate |
2011-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c47d39546752b7bebf88e76d69351f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf64a651d35e69cd92be84d229410069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cbe948ef1bd96a5a271fef4df34006a |
| publicationDate |
2012-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012048856-A1 |
| titleOfInvention |
Proinsulin with helper sequence |
| abstract |
The invention provides with a polypeptide comprising a proinsulin precursor and a helper sequence. The helper sequence enhances the expression of the proinsulin precursor in a recombinant organism and increases the yields of insulin after purification and processing of the insulin precursor. The invention is thus further concerned with a method of producing insulin, in which proinsulin is expressed as recombinant polypeptide in an organism such as E. coli, isolated from the organism and then processed to yield active insulin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10975376-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3312278-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013149729-A3 |
| priorityDate |
2010-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |