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filingDate 2010-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3c294d262de347dc0d213b89fe57160
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publicationDate 2012-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2012048451-A1
titleOfInvention Preparation process of (6r)-tetrahydrobiopterin hydrochloride
abstract A preparation process of (6R)-tetrahydrobiopterin hydrochloride is provided, which comprises hydrogenating L-biopterin in the presence of a catalyst of Pt group metal in the basic substrate containing solvent, potassium hydroxide and potassium dihydrogen phosphate to obtain (6R)-tetrahydrobiopterin hydrochloride, wherein the pH value of the basic substrate is controlled by potassium hydroxide and potassium dihydrogen phosphate in the range of about 10 to about 13.
priorityDate 2010-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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