| abstract |
Disclosed are compounds of the formula (I): wherein R 1 , R 2 , X, Y, and Z as described herein, or pharmaceutically acceptable salts thereof, for use in treating or preventing neurodegenerative diseases and disorders such as Huntington's disease. Also disclosed are pharmaceutical compositions comprising such compounds or pharmaceutically acceptable salts thereof and a pharmaceutically acceptable carrier and methods of treating or preventing neurodegenerative diseases and disorders. |