http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012042536-A3

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-14
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-32
filingDate 2011-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3adcd529eb08f6707e7d2c9b0a83104
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publicationDate 2012-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2012042536-A3
titleOfInvention A process for preparation of ether derivatives of dihdroartemisinin
abstract The present invention relates to a facile and cost-effective process for the preparation of ether derivatives of dihydroartemisinin. The present invention further enables preparation of pure β-ether derivatives of dihydroartemisinin, commonly known as Artemether, the methyl ether derivative and Arteether, the ethyl ether derivative, which are well-known antimalarial agents without using an organic pro-acid. This invention also discloses a novel epimerisation process for the a-ether derivatives of dihydroartemisinin in β- isomer.
priorityDate 2010-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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