Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12cfbf1b7f22f12a1e5e970fe151f79b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67f1970ad64be8ddf4dbc02844379869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ac449703cee1fe6cef4fc490b278181 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5d7e6d95705f2c4dc54c6e9e9eb8b14a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 |
filingDate |
2011-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c89bc695f29162541d2399adb54734f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f69069fc637024223230acafa6eee33a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c0709334e01c2e55c921ccc2962ab90 |
publicationDate |
2012-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2012034189-A1 |
titleOfInvention |
Methods of using mirnas transcribed from the 14q32 region of human chromosome 14 as biomarkers for schizophrenia or symptoms thereof |
abstract |
Provided herein are methods for detecting a risk profile for schizophrenia or a manifestation thereof or a sub-threshold phenotype or state thereof in a subject, comprising identifying a reduction or down regulation in expression of one or more miRNAs disclosed herein, or a molecule that regulates the expression of said miRNA, in blood from the subject wherein the reduction or down regulation of expression is indicative of a risk of the subject having or developing symptoms of schizophrenia. Also provided are methods of diagnosing schizophrenia based on the expression profiles of the miRNAs and miRNA regulatory molecules disclosed herein, and methods for treating schizophrenia by modulating the expression of said miRNAs and regulatory molecules. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105132525-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105132525-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104531703-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9856532-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014039893-A1 |
priorityDate |
2010-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |