Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92dd81bdd0d10ed3bc7807859a083297 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2011-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3b71a795c085630c0969293b6b0f927 |
publicationDate |
2012-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2012028718-A1 |
titleOfInvention |
Method for prognosing the age-at-onset of huntington's disease |
abstract |
The present invention relates to the prediction of the age-at-onset of Huntington's disease. More specifically, it relates to the use of at least one FoxO-centered network related biallelic markers, preferably single nucleotide polymorphism (SNP) markers, in particular GSK-3β and/or TCERG1 and/or FOXO1 and/or FZD10 related biallelic markers, for prognosing the age-at-onset of symptoms of Huntington's disease in an individual at risk of suffering from said disease. The invention also relates to lithium or a salt thereof for use at low doses in the treatment or prevention of Huntington's disease |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10571206-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10123464-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10330395-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10458724-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9803937-B2 |
priorityDate |
2010-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |