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filingDate 2011-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4fb27a84a5f5f9e14ff0825e7c3ee1e
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publicationDate 2012-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2012026723-A2
titleOfInvention Method for detecting metal ions using unnatural activity of nucleic acid polymerase, and logic gate using same
abstract The present invention relates to a method for detecting metal ions using unnatural activity of nucleic acid polymerase and a logic gate using same. More particularly, the present invention relates to a method for detecting mercury or silver using unnatural activity of nucleic acid polymerase which is induced by non-complementary thymine-mercury-thymine base pairs or cytosine-silver-cytosine base pairs formed through the specific binding between thymine-thymine base pairs and mercury ions or the specific binding between cytosine-cytosine base pairs and silver ions, and also relates to a logic gate using the method for detecting mercury or silver. According to the invention, the method for detecting metal ions using unnatural activity of nucleic acid polymerase can reduce cost and detect metal ions easily. The logic gate according to the present invention is cheaper than a conventional nucleic acid-based logic gate, which requires expensive RNA or chimeric DNA that lead to increased cost and has difficulty in practical application due to the system design thereof and operational difficulty, and can be practically applied as a molecular level logic gate capable of controlling a logic output signal.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021022574-A1
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priorityDate 2010-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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