http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012021046-A3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85d2ffe6cc308136b3cfd10090f74836 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b2d622df34eef7de7b665f9b3f98cad http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e58c686a219cb65f6325a60bc5272d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_259045c6eba6e2c5d338b84e0a88b571 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_229b537ccdf10497ecea2f6680605728 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L101-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 |
filingDate | 2011-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3cf69af97f0076ac5d0e9c388281580 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bf677f7d997d4a48ef50fa97b9dff68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a137c268ad5bd4eedeea85efed5485d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a93ac9d0dafe1ee4af64212eac71319 |
publicationDate | 2012-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2012021046-A3 |
titleOfInvention | Radial shape of polymer compound containing iodine, preparation method thereof, and ct contrast medium composition containing same |
abstract | The present invention relates to a radial shape of a polymer compound containing iodine capable of being used as an active ingredient of a CT contrast medium, a preparation method thereof, and a contrast medium composition containing the same. According to the present invention, the radial shape of the polymer compound containing iodine has a remarkably enhanced contrast effect retention time compared with a conventional low molecular weight contrast medium compound containing iodine. In addition, the polymer compound containing iodine forms a protective film by encompassing a compound containing iodine substituted near the surface of a central nucleus, which leaves room for causing various kinds of abnormal reactions with toxicity, with a relatively long biocompatible polymer chain layer, thereby preventing the exposure thereof to external environments to reduce in vivo toxicity, preventing the rapid absorption due to a macrophage to extend in vivo circulation time, and allowing the polymer compound containing iodine to be discharged from the body after an adequate time has passed since an in vivo injection. Further, the preparation method and the purification method of the polymer compound containing iodine are very simple, thereby enabling mass production in a high yield and at low costs, the polydispersity is very low, thereby providing high reproducibility in the preparation and effects, and all of the structures of the prepared radial shape of the polymer compound containing iodine comprise a covalent bond, thereby being structurally very stable, and thus the polymer compound containing iodine can be useful for the preparation of a CT contrast medium. |
priorityDate | 2010-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.