| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cdae492386dc00a8e36af9614326140f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5af91a4b9b1ddb91795165db30afdc88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a01717442a2a920617ac88dbdf9caacc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_478b2076865a94ee5217b4ece0feaadc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5f1148905df133f18a3f7b7bb9bf30f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-362
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-286
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
2011-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f50454a6174ee6e0bc6e0440d0f06f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96e0fcc6ad5f24b288ce62d14482f55a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3d5bf767eff2846cb074a57d27014d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e73e13d7323fceb4580224e79c377d1a |
| publicationDate |
2012-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012019291-A1 |
| titleOfInvention |
Preparation and purification of subunit vaccine for neisseria meningitidis (nm) group b isolates |
| abstract |
A method of preparing and purifying recombinant lipoprotein Ag473 of Neisseria meningitidis (NM) group B from Escherichia coii comprising disrupting cellular membranes of E.coli in the presence of a detergent, mixed-phase chromatography comprising silane-modified silica resin, anionic-exchange chromatography, cationic-exchange chromatography, and ultrafiltration. The methods can be used in large-scale production of vaccines for N. n meningitidis (NM) group B. Methods of preparing silane-modified-silica stationary phase resin are also disclosed. |
| priorityDate |
2010-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |