http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012011731-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d4b99ff0baaa5a19bf7fb12a3789191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6903e7231026c6b18a0a2aeeda91dd7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3893c2992fce60b04a82debd750db4c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
filingDate | 2011-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9ab835fd0db37c9a1a696cd57859415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9cbb9811061ec9b9234a369a0fe56f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02afc01f0c39ed550ef061af35bccc22 |
publicationDate | 2012-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2012011731-A2 |
titleOfInvention | Method for separating and identifying calgranulin a as a dementia marker from blood cells |
abstract | The present invention relates to a method for separating calgranulin A and β-actin as dementia markers which can be utilized in the diagnosis and treatment of dementia, and to a composition for the treatment and identification of dementia (Alzheimer's disease, vascular dementia, alcoholic dementia), comprising an antibody that specifically binds to the calgranulin A and to â-actin. The separation method of the present invention comprises the following steps: separating blood cells containing leucocytes (neutrophils, monocytes, macrophages, granulocytes, etc.), erythrocytes, platelets, and the like from blood; performing DEAE-cellulose column chromatography on the blood cells; precipitating the blood cells using 30 to 80% of ammonium sulfate; performing ubiquitin-Sepharose affinity column chromatography on the blood cells; performing electrophoresis on the blood cells; and checking the proteins of the blood cells. |
priorityDate | 2010-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 353.