| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0806b364d5c0879193a2553d98fb896d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6a963b74d428adc199eb6406f8e4ae2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c7ce4126455310065cda36189a8870e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62f941494409aea84f621977c5f0ab81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc2c2500f2bb8743d93b68ac7fda89d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1089
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0036 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 |
| filingDate |
2011-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50ad7f9de7229c0d7c92311c2e042e78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fc3dfebedfb55959186478f045ab1e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaf001521f97b25f34ac9e4eb2acdd32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0322090013a469d7bccbffe12ac9881a |
| publicationDate |
2012-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012009693-A1 |
| titleOfInvention |
Ancestral proteins |
| abstract |
The invention provides a method for increasing the stability and/or activity of a polypeptide at low pH and/or elevated temperatures. The invention further provides a method for increasing the melting termperature of a polypeptide. Also provided are paleoenzymologically reconstructed thioredoxin polypeptides having activity at higher temperatures and/or lower pH than extant thioredoxin polypepetides, as well as paleoenzymologically reconstructed thioredoxin polypeptides having higher melting temperatures than extant thioredoxin polypepetides. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110031583-A |
| priorityDate |
2010-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |