| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b7ebf4160a034531be2386823625e61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86e2cb88bad5425bb8a1c918271de5c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_213e7b98bce3a9d6be9936049694fa1a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41c54edeec7925423a8d3c2178621c92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66feaa0fb3ad2f3b27da5fbb6ee90ccd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_105e30116b125ab5cc02583fa4b44931
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_620cb8fa8188560ab8e512e10f6e3f10 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-36143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
| filingDate |
2011-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67363e6a85dee89522174cf61df8afb9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c615a6524fadefb8f1a1de834980a2ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_924ed4178735d5f8bbe6572925b47f5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d66ed672e796224e5f3e9def892f692
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fecf6d85be1a8d0232ea24fd4e17d019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97659bcdccc2c5a39a2579a682a99d61 |
| publicationDate |
2012-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2012001196-A2 |
| titleOfInvention |
Alphaviral vectors and the uses thereof for heterologous gene expression |
| abstract |
The invention relates to an alphaviral-replicon-based vector in which the sequence that encodes the structural polyprotein has been modified by means of a deletion in the region that encodes the capsid protein such that said sequence is incapable of producing a capsid protein capable of forming functional nucleocapsids. These vectors are capable of propagating to neighbouring cells in a manner dependent on the spicule proteins and are therefore suitable for heterologous gene expression in a cell or organism of interest. The invention likewise relates to virions that comprise the vector of the invention and also to methods for generating said virions and the use of the vector and of the virions for expressing heterologous proteins in a cell of interest and for therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105176936-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105176936-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2523016-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10011847-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014188042-A1 |
| priorityDate |
2010-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |