http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011162904-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_433e6c2a9282cbfc3410c7db7cf1aee9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9b6b96a0a91a8216a1201949494e156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0058 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06 |
| filingDate | 2011-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4082b803f388a2c19713ca7fd8d86d66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_998e74de614d6c9b5ca4bf07b7def30f |
| publicationDate | 2011-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2011162904-A2 |
| titleOfInvention | Multidomain biotags for cancer detection, diagnosis and therapy and methods of their use priority statement |
| abstract | A biotag for targeting a cancer biomarker is provided. The biotag may include a cancer biomarker binding domain, an internalization domain, an endosomal escape domain, a lysosomal escape domain, a reporter binding domain, and a reporter, wherein the reporter is a diagnostic agent. The cancer biomarker can be ERBB 1-4, EGFRvlH or Transferrin Receptor (TfR). The binding domain can be an scFv, an sdFv, a CDR or an SDR modified CDR. The reporter binding domain is a metal binding domain, which may be chelated to a metal nanoparticle tag. The metal nanoparticle tag is a noble metal, a superparamagnetic metal, a core-shell nanoparticle, or a fluorescent agent. A targeted contrast composition for use with a diagnostic imaging technique is provided, which includes a contrast agent and a biotag for targeting a cancer biomarker. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9506925-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9885718-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10620209-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022227846-A1 |
| priorityDate | 2010-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1145.