Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42cfe32b959cbb86b8c45a157a122cb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79653a8570a0b9695431f3a42d5d328a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_85d8c2192741366501076053bf7b6736 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_910f66bacb2772dde50a8901ad792961 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6edb5285b39ab61950d1341a0eb9045f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26676a113b8415357271c6071172bd5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_701f371ee172158f7658a514cf73b464 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2077 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-209 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-57 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 |
filingDate |
2011-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d919b311c8deaf797c4b385a7878523f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad86beb9f017036935b31ae7afe52303 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dde2547aad293be811360559edacbb69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc4ee3e756aaad36f9614e49d114b5aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03aa6dc3162c010edae802efb05c1772 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5bef75ce5ce7bb59332f5aa56423790 |
publicationDate |
2012-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011160136-A3 |
titleOfInvention |
Progesterone containing oral dosage forms and related methods |
abstract |
The present invention provides for progesterone containing pharmaceutical oral dosage forms and related methods. The oral dosage forms can each include an amount of progesterone as well as a pharmaceutically acceptable carrier. The oral dosage forms can be formulated to have at least one of the following characteristics: the oral dosage form produces an pregnane metabolite mean blood plasma level of less than about 1000 nmo1/L; the oral dosage form produces an pregnane metabolites mean blood plasma level, after administration of single dose of progesterone composition, such that the ratio of pregnane metabolite level to parent progesterone level of less than 10: 1; has a dissolution rate in vitro, when measure using a USP Type-1 dissolution apparatus in 900 mL of deionized water with 2.0 % (w/v) of sodium lauryl sulfate at 100 rpm, such that the oral dosage form releases at least 10 wt% of the progesterone within the first 30 minutes and/or releases less than 45 wt% in the first 4 hours; and the oral dosage form produces a ratio of mean plasma progesterone AUC to the amount of progesterone administered of more than 1.5x10-6 hr/mL:1. |
priorityDate |
2010-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |