| abstract |
Disclosed is a novel factor KIAA1199 that participates in the decomposition of hyaluronic acid, and also disclosed is the use thereof. Specifically disclosed are: a hyaluronic acid decomposition promoter comprising the KIAA1199 gene and protein thereof; a hyaluronic acid decomposition inhibitor (comprising siRNA or monoclonal antibody) that inhibits the activity or expression of the hyaluronic acid decomposition promoter; and a method for screening for a novel hyaluronic acid decomposition inhibitor using KIAA1199 expression as the indicator. |