abstract |
This invention relates to a method for identifying an anti-ageing agent for use in skincare compositions, by determining the ability of a material or combination of materials to modulate the expression of molecules associated with microfibril or elastic fibres. More specifically, the invention relates to a method for identifying an anti-ageing agent by determining the ability of a material or combination of materials to modulate LOXL-1, LTBP-2 and/or LTBP-3 expression. The invention also relates to methods for assessing the anti-ageing effect of a material or combination of materials on the skin, anti-ageing agents identified by such methods, and compositions containing them. |