Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_647ff70184e72c3d6ba0be2195e860e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77dfe7c9e4b97893fc78adae1eebcf9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae765265ce08d7ac8dd9905b138338a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fda969a77ec09fb2ad29117fcc07d154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3155069b833b184bcd4ad12f7100dd4c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 |
filingDate |
2011-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3ac5e1ecac836e3b75fc517e95a60c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d4a75988c7c891af74a4429bf36f54b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c481e255c73086aa3cd87d6aca3bc8d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56a61e29d12096e92685310f04bb3d53 |
publicationDate |
2011-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2011150086-A2 |
titleOfInvention |
Diagnosis and treatment of autoimmune disease |
abstract |
The detection of parietal cell autoimmune antibodies comprising an ATP4A D3.2 subdomain binding site can diagnose autoimmune body gastritis and/or pernicious anemia with extraordinary sensitivity and specificity that is far superior to existing commercial assays. Further, the assay has diagnostic applications for use in diagnosing type 1 diabetes, thyroiditis and Addison's disease. As pernicious anemia is typically a disease of the elderly, detection of parietal cell antibodies may precede clinical disease by many years if not decades, thereby allowing the initiation of therapeutic interventions such as vitamin B12 administration to prevent the development of pernicious anemia or immunologic interventions to prevent type 1 diabetes and its complications. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3671212-A2 |
priorityDate |
2010-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |