| abstract |
Disclosed herein are methods for diagnosing lung carcinoma type in a subject by differentiating subtypes of non-small cell lung carcinoma (NSCLC), for example, diagnosing a squamous cell type lung carcinoma or a non-squamous type lung carcinoma in the subject. In some embodiments, the methods include determining a first amount of serpin B13 protein in the sample, determining a second amount of cytokeratin 5 and/or cytokeratin 6 protein in the sample, determining a third amount of thyroid transcription factor- 1 protein in the sample, and determining a fourth amount of napsin A protein in an NSCLC sample. In some embodiments, the methods further include determining a fifth amount of p63 protein in an NSCLC sample. In other embodiments, the methods include determining a first amount of cytokeratin 5 and/or cytokeratin 6 protein in the sample, determining a second amount of thyroid transcription factor- 1 protein in the sample, and determining a third amount of napsin A protein in an NSCLC sample. |