abstract |
The present invention is directed to a stable pharmaceutical formulation comprising telmisartan, or a pharmaceutically acceptable salt thereof/ and a diuretic dispersed in a matrix. The matrix comprises at least one disinte grant in an amount ranging from 0.5 % to 20% by weight; a dissolution enhancing agent present in a molar ratio of dissolution enhancing agent to telmisartan of from 1:1 to 10:1; a water-insoluble diluent in an amount ranging from 15%-75% by weight and at least one other pharmaceutically acceptable excipient /or adjuvant in an amount ranging from 0 - 25% by weight, |