http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011143292-A1

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filingDate 2011-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_038473788171e3514198149c5b704b46
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publicationDate 2011-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2011143292-A1
titleOfInvention Biomarkers for detecting erythropoietin use in human subjects
abstract Erythropoietin (Epo) is produced primarily in the kidneys upon low blood oxygen tension and stimulates erythropoiesis in the bone marrow. Recombinant human Epo (rHuEpo), a drug developed to increase arterial oxygen content in patients, is expensive and optimal dosing is difficult to determine and which can lead to waste. RHuEpo is also illicitly used by athletes to improve endurance performance. Described herein are methods for detecting exogenous Epo presence in a human subject by detecting an aberrant level of a biomarker such as isoforms of haptoglobin, transferrin, and/or hemopexin/albumin in serum samples.
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