| abstract |
Compounds having a structure of the formula (I) and pharmaceutically acceptable salt, preparation method and use thereof are disclosed, wherein R is nitrile. The compounds of the present invention have anti-platelet aggregation activity and can be used in the manufacture of the medicine for the treatment or prevention of cardiac and cerebral vascular diseases such as coronary artery syndromes, myocardial infarction and myocardial ischemia caused by platelet aggregation. |